Dr. Lam is an Associate Professor of Neurosurgery at the University of Minnesota. He received his B.S. degree from the University of Denver in 1983 and his M.D. degree from the University of Colorado in 1987. Following two years of surgery at Beth Israel Hospital of Boston, he completed his neurosurgical residency at McGill University's Montreal Neurological Institute. During his training he was the Preston Robb Fellow and performed research on excitatory amino acids and basal ganglia development. He went on to Montreal Children's Hospital for his pediatric neurosurgery fellowship before coming to the University of Minnesota.

Dr. Lam's complete CV

Dr. Lam's Experts@Minnesota Information

Craniofacial anomalies

• Cellular approaches to reduce BMT complications
  Co-investigator, PI: Bruce Blazar, MD, PhD, 2004
• Enzyme replacement therapy effects on brain pathology in the murine model of Hurler syndrome
  Co-investigator (section: craniofacial morphometrics), PI: Jakob Tolar, MD, PhD, 2004
• Craniofacial anomalies in the mucopolysacharidosis I mouse
  Co-Principal Investigator, co-PI: Chet Whitley, MD, PhD, 2003
• Craniosynostosis model in the rat
  Principal Investigator, 1999

Pediatric epilepsy

• Source Analysis of Epileptic Activity
  Site Principal Investigator, Allina Hospitals, PI: Bin He, PhD, 2005
• Early Randomized Surgical Epilepsy Trial (ERSET)
  Co-investigator, local PI: Thaddeus Walczak, MD, MINCEP multicenter randomized controlled study: NINDS #NS42372, 2003-5
• Valproic acid and its effect on hippocampal slices
  Investigator, PI: Howard Blume, MD, PhD, 1989-91

Neurotransport and cerebrospinal fluid dynamics

• Vascular Genomics of Human Brain
  Co-Investigator, PI: Lester Drewes, PhD, 2005
• Cerebellar tissue analysis in individuals with Arnold Chiari Malformation Type I
  Co-Principal Investigator, PI: Christopher Gomez, MD, PhD, 2004
• The murine leptomeningeal cell culture
  Principal Investigator, 2004

Additional projects

• DuraSeal Sealant Post Market Study – Confluent Surgical Inc.
  Co-investigator, PI: Stephen Haines, MD, 2005
• The Park-Reeves Syringomyelia Research Consortium
  Co-investigator, local PI: Daniel Guillaume, MD, 2012

• 1/1/12 – 12/31/12, Institute for Engineering in Medicine, Probing and Manipulating Vascular Endothelial Cell membranes using Nanowires; role: co-PI (along with Bethanie Stadler, PhD), Institute of Engineering in Medicine Seed Grant Program ($40,000)
• 4/1/2012 – 3/31/16, VA Merit Review Application, CSF Clearance of Intracranial Debris from Traumatic Brain Injury; role: PI, 25%
• ($604,708, direct cost)
• 2/10/2013 – no end date, Institute for Engineering in Medicine, Nanotechnology Development and Applications for Clinical Neurosicence Applications; role: co-I (PI: Jian-Ping Wang PhD, Walter Low PhD, $75,000)

• 1996, Resident representative, Board of Directors, Montreal Neurological Institute, McGill University, Montreal
• 1997, Member, Brain Tumor Center Accreditation Board, Montreal Neurological Hospital, McGill University, Montreal
• 1998, Member, Cancer Research Center, Minneapolis, University of Minnesota
• 1998, Co-director, City-wide Pediatric Neurosurgery Conference, University of Minnesota
• 2000, Member, Child Abuse and Neglect Committee, University of Minnesota
• 2000, Member, Search Committee for the Chair in Pediatric Brain Tumors, University of Minnesota
• 2003, Member, Search Committee for the Chair in Neurological Surgery, University of Minnesota
• 2003, Member, Committee on the Safety of Deep Brain Stimulators, Medtronic Inc.
• 2003, Chairman, Curriculum Committee for Neurosurgery Resident Education
• 2003, Member, Search Committee for the Chief in Pediatric Neurology, University of Minnesota
• 2004, Member, Search Committee for Research Associate, Neurosurgery, University of Minnesota
• 2005, Executive member, Neural Tissue Engineering and Devices Interest Group,Biomedical Engineering Institute
• 2005, Member, Biomedical Engineering Imaging Interest Group, Biomedical Engineering Institute
• 2005, Member, Dean’s Task Force on Admissions, University of Minnesota School of Medicine
• 2005, Member, Biomedical Engineering Institute
• 2007, Member, Task Force on Lumbo-sacral imaging, Minneapolis Veterans Administration Hospital
• 2013, Member, Fluoroscopy Safety Committee, Minneapolis Veterans Administration Hospital
• 2013, Member, Functional and Stereotactic Neurosurgeon Search Committee, University of Minnesota

• Hornbeck Academic Achievement Award, Denver University, 1980, 1981, 1982
• Award for High Achievement in Independent Research, Denver University, 1983
• Honors in Chemistry, Denver University, 1983
• Phi Beta Kappa, 1983
• George B Packard Award in surgery, University of Colorado, 1987
• Harris Yett Award in Clinical Orthopaedics, Beth Israel Hospital, Harvard University, Boston, 1988
• Third Prize, Visiting Professor's Research Award, Beth Israel Hospital, Harvard University, Boston, 1989
• Preston Robb Scholar, McGill University, Montreal, 1995
• President, Montreal Neurological Institute Fellow’s Society, McGill University, Montreal, 1996
• Penfield McNaughton Award for Outstanding Resident in Neurosurgery, McGill University Neurosurgery residency program, Montreal, 1997
• Herz Foundation Faculty Teaching Development Award 2004
• Regent’s scholarship, University of Minnesota, 2005 – 2011
• Dr. and Mrs. Scott Augustine Endowment for the MDMS program, 2005 – 2006
• Marquis Who’s who in Medicine and Healthcare, 2006
• Nominee, 7th Annual Medical Staff Award for Clinical Excellence, Twin Cities Veterans Administration Medical Center, 2008
• Mentor for Hydrocephalus Association Resident Presentation Award winner – Christopher G. Janson, MD, 2009
• Mentor for VA Zieve Resident Research Award winner – Christopher G. Janson, MD, 2010

JOURNAL ARTICLES

1. Lam CH, Dubuisson D: Treatment of hemispheric collapse and herniation beneath the falx in a case of shunted hydrocephalus. Surg Neurol 33(3):202-205, 1990. Abstract (HTML) 
2. Lam CH, Cosgrove GR, Drislane FW, Sotrel A: Spinal leptomeningeal metastasis from cerebral glioblastoma. Appearance on magnetic resonance imaging. Surg Neurol 35(5):377-380, 1991. Abstract (HTML) 
3. Lam CH, Farmer JP, Meagher-Villemure K, Montes JL: Masson's vegetant haemangio-endothelioma. Pediatr Neurosurg 23(2):93-96, 1995. Abstract (HTML) 
4. Lam CH, Ethier R, Pokrupa R: Conservative therapy of atlantoaxial osteomyelitis. A case report. Spine 21(15):1820-1823, 1996. Abstract (HTML) 
5. Lam CH, Montes J, Farmer JP, O'Gorman AM, Meagher-Villemure K: Traumatic aneurysm from shaken baby syndrome: case report. Neurosurgery 39(6):1252-1255, 1996. Abstract (HTML) Full Text (PDF) 
6. Lam CH, Stratford J: Bilateral hypoglossal nerve injury with occipital condylar fracture. Can J Neurol Sci 23(2):145-148, 1996. Abstract (HTML) 
7. Lam CH, Villemure JG: Comparison between ventriculoatrial and ventriculoperitoneal shunting in the adult population. Br J Neurosurg 11(1):43-48, 1997. Abstract (HTML) 
8. Lam CH: A theory on the embryogenesis of oculo-auriculo-vertebral (Goldenhar) syndrome. J Craniofac Surg 11(6):547-552, 2000. Abstract (HTML) 
9. Lam CH, Solomon RK, Clark HB, Casey SO: Reversal of increased intracranial pressure with removal of a torcular epidermoid: case report. Neurosurgery 48(4):929-932, 2001. Abstract (HTML) Full Text (PDF) 
10. Lam CH, Hall WA, Truwit CL, Liu H: Intra-operative MRI-guided approaches to the pediatric posterior fossa tumors. Pediatr Neurosurg 34(6):295-300, 2001. Abstract (HTML) 
11. Rustamzadeh E, Truwit CL, Lam CH: Radiology of nonaccidental trauma. Neurosurg Clin N Am 13(2):183-199, 2002. Abstract (HTML) 
12. Lam CH, Nagib MG: Nonteratomatous tumors in the pediatric sacral region. Spine 27(11):E284-287, 2002. Abstract (HTML)
13. Lam CH, Horrigan M, Lovick DS: The Seldinger technique for insertion of difficult to place ventricular catheters. Pediatr Neurosurg 38:90-93, 2003. Abstract (HTML) 
14. Anderson, C, Graupman, P.C., Hall, W.A., Sweeny, M., Lam, C.H., Pediatric intracranial complications of central venous catheter placement – case reports. Pediatr Neurosurg. 2004;40:28-31.
15. Graupman, P.C., Pan D, Konair B, Hartung S, McIvor S, Whitley C, Low, W., Lam, C.H., Craniofacial abnormalities in a murine knock-out model of mucopolysaccharidosis IH: A computed tomography and anatomic study, J. Craniofacial Surgery 2004;15(3):392-398.
16. Lam, C.H., Sethi, K.A., Low, W., A morphometric, neuroanatomic and behavioral study on the effect of geometric constraint on the growing brain: the methyl-2-cyanoacrylate craniosynostosis model. Journal of Neurosurgery: Pediatrics 2005;102(4):396-402.
17. Kushen, M., Gulbache, E., Lam, C.H., Ewing’s sarcoma of the cavernous sinus: case report. Neurosurgery 2005;56(6):1375.
18. Rustamzadeh, E., Graupman P.C., Lam, C.H., Split brain malformation. Journal of Neurosurgery: Pediatrics 2006;104(5);362-365.
19. Shieh, C., Lam, C.H., A lateral cervical lipomyelomeningocele associated with diplomyelia. Pediatric Neurosurgery 2006;42(6):399-403.
20. Vatassery G., Lam, C.H., Smith W.E. Quach H.T. Apolipoprotein E exerts selective and differential control over vitamin E concentrations in different areas of mammalian brains. J of Neuroscience Research 2007;84(6):1335-42.
21. McClelland S. III, Won E.K., Lam C.H., Utilization of recombinant activated factor VII for intracranial hematoma evacuation in coagulopathic nonhemophilic neurosurgical patients with normal international normalized ratios. Neurocritical Care. 2007;7(2):136-9.
22. McClelland S. III, Charnas L.R., Santa Cruz K.S., Garner H.P., Lam C.H. Progressive brainstem compression in an infant with neurocutaneous melanosis and Dandy-Walker complex following ventriculoperitoneal shunt placement for hydrocephalus. case report. Journal of Neurosurgery: Pediatrics 2007;107(6):500-503.
23. Shamji, M.F., Vassilyadi M., Lam, C.H., Montes, J.L., Congenital tumors of the central nervous system, the Montreal Children’s Hospital experience. Journal of Neurosurgery: Pediatrics 2009;45(5):368-375.
24. Janson C., Romanova L., Hansen E., Hubel A., Lam C., Immortalization and functional characterization of rat arachnoid cells, Neuroscience 2011; Mar 17;177:23-34.
25. Lam, C.H., Hansen E.A., Hubel A., Arachnoid cells on culture plates and collagen scaffolds: phenotype and transport properties, Tissue Engineering Part A 2011, Jul:17(13-14):1759-66.
26. Conway A., Wiernik A., Rawal A., Lam C., Mesa H., Occult primary medullary thyroid carcinoma presenting with pituitary and parotid metastases: case report and review of the literature, Endocrine Pathology 2012, Jun;23(2):115-22.
27. Lam, C.H., Hansen E.A., Janson C., Bryan A., Hubel A., The characterization of arachnoid cell transport II: paracellular transport and blood CSF barrier formation of arachnoid cells, Neuroscience 2012; Oct 1 1;222:228-38.
28. Lam, C.H., Hansen E.A., Hall W., Hubel A., Application of transport phenomena analysis technique to cerebrospinal fluid, J Neurosurgical Science. (accepted)
29. Norby K.E., Qaiser R., Lam, C.H., A 12-year-old Girl with an Extraosseous Chondrosarcoma, J Neurology Research. (accepted)
30. Anirudh S., Hein,M., Zhu, Y., Thor, S, Hubel, A., Cobian, R., Reddy, M., Tan, L., Hansen, E., Lam, C. Orlowski, G, Stadler, B.J.H., Manipulations of Cells using Au-capped Ni Nanowires, Transactions on Magnetics – Conferences. (submitted)
31. Park, H.J., Clark, B., Lam, C.H., PET positive benign sacral schwannomas, J of Neurosurgery (in progress)
32. Lam, C.H., Jones, K.E., Clark, B., Scarring in the Neuraxis, Clinical Neurology and Neurosurgery (in progress)

Books and Chapters

1. Rustamzadeh E., Lam, C.H., Managing hydrocephalus with shunting devices, in The Bionic Human, ed. F.E. Johnson and K.S. Virgo, Humana Press, 2005.
2. Sherr G., Lam, C.H., iMRI Shunt Placement, in Intra-operative MRI-Guided Neurosurgery, ed. W.A. Hall, C. Nimsky, and C.L. Truwit, Thieme Publishing, 2010.
3. Lam, C.H., The Egress of Fluid from the Brain via Arachnoid Transport: Foundational Work for the Tissue Engineering of the Arachnoid Granulation, PhD thesis, University of Minnesota, 2011

Abstracts and Presentations

1. Lam, C.H. The energetics of BrN3, Proceedings of the American Chemical Society, Boulder, Colorado, 1983
2. Lam, C.H., Villemure, J.-G. Comparison between ventriculo-atrial and ventriculo-peritoneal shunting in the adult population, Congrès des Sciences Neurologiques, Montreal, Quebec, 1992
3. Lam, C.H., Olivier, A. Re-extension of corpus callosotomy, Congrès des Sciences Neurologiques, Montreal, Quebec, 1992
4. Lam, C.H., Olivier A., Re-extension of corpus callosotomy, Proceedings of the American Epilepsy Association, Seattle, Washington, 1992
5. Lam, C.H., Ethier R., Pokrupa R. Radiologic findings in atlanto-axial osteomyelitis, 56th Scientific Meeting of the Canadian Association of Radiologist, Quebec City, Quebec, 1993
6. Lam C.H., Sadikot, A.F., Fortin, M., Olivier, A., Parent A. Immunohistochemical distribution of calretinin in the primate amygdala. Society of Neurosciences, Miami, Florida, 1994
7. Lam, C.H., Sadikot, A.F., Development of subcortical pathways in the mammalian basal ganglia: the thalamostriatal projection. Pediatric section of the American Association of Neurological Surgeons, St. Louis, Missouri, 1994
8. Lam, C.H., Sadikot, A.F., Prenatal development of NMDA receptor subtypes in the rat striatum. Society of Neurosciences, San Diego, California, 1995
9. Lam, C.H., Sadikot, A.F., NMDA receptor subtype expression in the periventricular germinal matrix: a possible role in intraventricular hemorrhage. American Association of Neurological Surgeons, Minneapolis, Minnesota, 1996.
10. Alonzo-Vanegas, M., Olivier, A., Lam, C.H., Corpus callosotomy for the treatment of drop attacks. American Association of Neurological Surgeons, Minneapolis, Minnesota, 1996.
11. Srivastava, V., Alonso-Vanegas, M.A., Lam, C.H., Higgins, M.J., Ventureyra, E.C.G., Surgical management of simple craniosynostosis at the Children’s Hospital of Eastern Ontario. Canadian Congress of Neurological Sciences, London, Ontario, 1996.
12. Lam, C.H., Sadikot, A.F., Metabotropic receptor mRNA expression in the rat striatum following decortication during development. Society of Neurosciences, Washington, D.C., 1996.
13. Srivastava, V., Lam, C.H., Sadikot, A.F., Development of the thalamostriatal projection to the striatum in the prenatal and postnatal rat. Society of Neurosciences, Washington, D.C., 1996.
14. Alonso-Vanegas M.A., Lam, C.H., Mendizabal R., Sanchez-Cabrera J.M., Surgical treatment of primary empty sella syndrome, American Association of Neurological Surgeons, Denver, Colorado, 1997.
15. Lam, C.H., Nagib M.G., Non-teratomatous sacral tumors in the pediatric population, Pediatric section of the American Association of Neurological Surgeons, Atlanta, Georgia, 1999.Lam, C.H., Nagib M.G., Non-teratomatous sacral tumors in the pediatric population, American Society of Pediatric Neurosurgeons, Hawaii, 2000.
16. Sethi, K., Low W., Lam, C.H., Craniosynostosis in the perinatal rat using a cyanoacrylate model: a neuroanatomic study, Eleventh Iowa-Minnesota University Neurosurgery Conference, Minneapolis, 2000.
17. Graupman P., Lam, C.H., Basicranial diastematomyelia: an extension of the split cord malformation concept, Congress of Neurological Surgeons, San Antonio, Texas, 2000.
18. Sethi, K., Low W., Lam, C.H., Craniosynostosis in the perinatal rat using methyl-2-cyanoacrylate: a neuroanatomic study, Pediatric section of the American Association of Neurological Surgeons, San Diego, 2000
19. Lam, C.H., Lovick, D.S., The Seldinger technique for multiloculated ventricles and difficult shunt placements, Pediatric section of the American Association of Neurological Surgeons, New York, 2001
20. Lam, C.H., Ventriculomegaly, arrested hydrocephalus, and compensated hydrocephalus, American Society of Pediatric Neurosurgeons, Nevis, 2002.
21. Preciado D.A., Lam, C.H., Rimell, F., Temporal craniectomy for pediatric cochlear implant securement, American Society of Pediatric Otolaryngologists, Boca Raton, 2002.
22. Sethi K.A., Chu R.M., Tummala R.P. Lam, C.H., Craniosynostosis in the perinatal rat with the use of Methyl-2-Cyanoacrylate: a neuroanatomic study, Congress of Neurological Surgeons, Philadelphia, 2002.
23. Horrigan, M., Lovick, D.S., Lam, C.H., The Seldinger technique for multiloculated ventricles and difficult shunt placements, University of Minnesota School of Medicine Student Research Day, Minneapolis, 2003.
24. Graupman, P., Low, W., Lam, C.H., Craniofacial anomalies of the mouse model of mucopolysaccharidosis., Fourteenth Iowa-Minnesota University Neurosurgery Conference, Iowa City, 2003.
25. Walczak T., White, J., Beniak, T., Tran, T., Leppik I., Beattie, J., Lam, C.H., Maxwell R., Gumnit, R.J., Standard anterior temporal lobectomy does not resect the entire seizure onset area in temporal lobe epilepsy with normal MRI, American Academy of Neurology, San Francisco, 2004.
26. Lam, C.H., Xiao, J., Low, W.C., Cellular substrate for the study of CSF transport: mouse leptomeningeal cell culture, Pediatric section of the American Association of Neurological Surgeons, San Francisco, 2004.
27. White J.R., Leppik I.E., Walczak T.S., Beattie J.L., Matchinsky D.J., Tran T., Rarick J., Lam C.H., Felbamate: clinical and laboratory characteristics in long-term users, American Epilepsy Society, New Orleans, 2004.
28. Eastlund T., Jax K., Chipman J., Lam C., Mair D., Three confirmed cases of TRALI from plasma transfusions during one year at a medium sized hospital, American Association of Blood Banks, Washington D.C., 2005.
29. Lam, C.H., Xiao, J., Low W.C., Differential growth pattern of arachnoid cell culture on extracellular matrix, Pediatric section of the American Association of Neurological Surgeons, Orlando, Florida, 2005.
30. White J.R., Leppik I.E., Walczak T.S., Beattie J.L., Matchinsky D.J., Tran T., Rarick J., Lam C.H., Felbamate: Clinical and laboratory characteristics in long-term users, Meeting of the American Academy of Neurology, Miami, Florida, 2005.
31. Lam, C.H., Hansen E.A., Hubel A., Arachnoid cell behavior on three dimensional collagen scaffolds, Society of Neuroscience, Chicago, Illinois, 2009.
32. Lam, C.H., Hansen E.A., Hubel A., Transport Properties of Arachnoid cells, American Association of Neurological Surgeons – Pediatric section, Boston, Massachusetts, 2009.Lam, C.H., Hansen E.A., Hubel A., Growth and Morphometrics of Arachnoid Cells on Collagen Scaffolds, American Association of Neurological Surgeons – Pediatric section, Boston, Massachusetts, 2009.
33. Janson C.G., Hansen E.A., Hubel A., Lam, C.H., Immortalization of Arachnoid cells, American Association of Neurological Surgeons – Pediatric section, Boston, Massachusetts, 2009.
34. Bryan A.D., Hansen E.A., Hubel A., Lam, C.H., An Apparatus to Study Cells under Constant Pressure, Life Science Alley Conference and Expo, Minneapolis, MN, 2009.
35. Janson C.G., Hansen E.A., Hubel A., Lam, C.H., Immortalization of Arachnoid cells and its Transport Character, Minneapolis VA Research Day, Minneapolis, 2010
36. Lam C.H., Hansen E.A., Hubel A., The Characterization of Arachnoid Cell Transport. Society of Neuroscience, San Diego, California, 2010
37. Hansen E.A., Lam C.H., Hubel A., The Transport Properties of the Immortalized Rat Arachnoid Cell Line, Society of Neuroscience, San Diego, California, 2010
38. Lam C.H., Hansen E.A., Hubel A., The effects of Calcium Modulation on the Paracellular Transport in Arachnoid Cells, Society of Neuroscience, Washington D.C., 2011
39. Hansen E.A., Lam C.H., Hubel A., cAMP and the Arachnoid Blood CSF Barrier, Society of Neuroscience, Washington D.C., 2011
40. Norby K., Qaiser R., Lam C.H., A 12 year old girl with an extraosseous chondrosarcoma, Gillette Pediatric Neuroscience, Minneapolis, 2012
41. Lam, C.H., Hubel A., Yuan C., Norby K.E., Hansen E.A., The effect of blood and blood breakdown products on the arachnoid egress blood-CSF-barrier, Society of Neuroscience, New Orleans, LA, 2012.
42. Hansen E.A., Hubel A., Yuan C., Norby K.E., Lam C.H., The influence of fibroblast on the arachnoid blood-CSF-barrier, Society of Neuroscience, New Orleans, LA, 2012.
43. Sharma, A., Zhu, Y., Hansen, E., Hein, M., Thor, S., Lam, C.H., Hubel, A., Stadler, B., Manipulation of Cells using Au-capped Ni Nanowires, invited talk, 12th Joint MMM/Intermag Conference, Chicago, IL, 2013.
44. Hein, M., Sharma, A., Hansen E., Lam, C., Stadler B., Nanowire Enhanced Cell Permeability, Materials Research Society, San Francisco, 2013 (accepted). 

• Pediatric neurosurgery
• Epilepsy
• Hydrocephalus
• Spina bifida
• Tethered spinal cord
• Craniofacial disorders
• Brain tumors
• Cysts in children

• Congress of Neurological Surgeons
• Minnesota Medical Association
• Hennepin Medical Society
• Minnesota Neurosurgical Society
• American Association of Neurological Surgeons
• Pediatric section, American Association of Neurological
• Surgeons and Congress of Neurological Surgeons
• American Cleft Palate-Craniofacial Association
• Minnesota Medical Association Committee on Accreditation and Continuing Medical Education, 2005 – 2007
• American Association of Advancement of Science
• Society of Neuroscience