Stephen J. Haines, MD, FACS

Professor, Department of Neurosurgery

Stephen J. Haines

Contact Info

shaines@umn.edu

Mailing Address:
MMC 96
420 Delaware St. SE
Minneapolis, MN 55455

Administrative Assistant Name
Deb Fellows

Administrative Phone
612-626-8786

Administrative Email
fello062@umn.edu

Professor, Department of Neurosurgery


Neurosurgeon, Pediatric Neurosurgeon


MD, University of Vermont, College of Medicine, Burlington, VT

Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA

Fellowship in Clinical Trials, Oxford University, Oxford, England

AB, Dartmouth College, Hanover, NH

Summary

Professor Stephen Haines received his MD from the University of Vermont and completed his residency in neurosurgery at the University of Pittsburgh. He was the 1981 Van Wagenen Fellow of the American Association of Neurological Surgeons. Prior to his appointment at the University of Minnesota, he was the Department of Neurological Surgery Chairman and a founding Co-Director of the Neuroscience Institute at the Medical University of South Carolina. He was board certified in Neurological Surgery in 1984. 

From 2003 to 2017, Dr. Haines served as the Lyle A. French Chair in Neurosurgery and Head of the Department of Neurosurgery at the University of Minnesota.

His clinical interests are in surgery of the posterior fossa and cranial nerves, open and endoscopic skull base surgery and pediatric neurosurgery. He has an active practice in trigeminal neuralgia, complex hydrocephalus, the treatment of Chiari malformations, and adults with congenital structural abnormalities of the nervous system.

Dr. Haines’ primary research interest focuses on applying advanced clinical research techniques to neurosurgery and developing resources for the evidence-based practice of neurosurgery. He has published and lectured extensively on these subjects. He is a past member of the Editorial Board of the Cochrane Stroke Group and has led his department's involvement in numerous clinical trials.

Awards & Recognition

  • Best Doctors in America 2000-2018
  • Mpls.St.Paul Magazine "Top Doctor," 2012-2018
  • Fellow of the American Association of Neurological Surgeons, Harvey Cushing Society, July 2010
  • University of Vermont Medical Alumni Association’s Distinguished Academic Achievement Award, 2010
  • Honorary Membership, American Society of Pediatric Neurosurgery, 2008
  • Who's Who in America, 2004 – present
  • Best Doctors in America, 2000 – present
  • Who's Who in Medicine and Healthcare, 1998 – present
  • William P. Van Wagenen Fellowship, American Association of Neurological Surgeons, 1981

Professional Associations

  • Alpha Omega Alpha
  • American Academy of Neurological Surgeons
  • American Association of Neurological Surgeons 
  • American Association of Neurological Surgeons - Pediatric Section 
  • American College of Surgeons 
  • American Medical Association 
  • American Society of Pediatric Neurosurgeons, honorary member
  • Congress of Neurological Surgeons
  • International Brain Barriers Society
  • International Society for Pediatric Neurosurgery
  • International Society for the Pediatric Skull Base 
  • Minnesota Neurosurgical Society 
  • Minnesota Society for Neurological Sciences
  • Neurosurgical Society of America
  • North American Skull Base Society 
  • Society of Neurological Surgeons
  • Trigeminal Neuralgia Association 
  • Hemifacial Spasm Society

Research

Research Summary/Interests

Dr. Haines’ primary research interest focuses on applying advanced clinical research techniques to neurosurgery and developing resources for the evidence-based practice of neurosurgery. He is a past member of the Editorial Board of the Cochrane Stroke Group and has led his department's involvement in numerous clinical trials. He has published and lectured extensively on these subjects.

Evidence-based Neurosurgery

Improving the quality of clinical research in neurosurgery has been a consistent theme throughout Dr. Haines' career. He has documented the methodological inadequacy of much of the clinical research literature in neurosurgery and disseminated information about applying more modern and appropriate techniques. Over time, this interest has broadened, in parallel with the development of clinical epidemiology and evidence-based medicine, into applying the principles of evidence-based medicine to neurosurgery. Current work continues the emphasis on dissemination with recent publication about methods of teaching evidence-based neurosurgery to clinically active neurosurgical residents and ongoing work on a text of principles and examples of evidence-based neurosurgery, as well as promoting departmental participation in clinical trials. Future interests include developing small sample size analysis techniques and using a rigorous methodology to determine indications for and safety of neurosurgical procedures.

Neurosurgical Infection

A second theme running through Dr. Haines' research career has been the clinical investigation of neurosurgical infection. Studies have included risk factors for neurosurgical infection, neurosurgical antibiotic prophylaxis, and the clarification of the role of propionibacter acnes in shunt infection.

Research Funding Grants

  • Randomized Controlled Study to Evaluate the Efficacy and Safety of Fibrin Sealant, Vapour Heated, Solvent/Detergent Treated (FS VH S/D 500 s apr) Compared to DuraSeal Dural Sealant as an Adjunct to Sutured Dural Repair in Cranial Surgery; role: Principal Investigator; funded by Baxter Healthcare Corporation (11/1/17 – 10/31/19)
  • MnDRIVE Brain Conditions Innovations Grant, “Complex Oro-Facial Pain: Functional Imaging Characterization and Treatment with Transcranial Magnetic Stimulation;” role: Principal Investigator (2015 - present)
  • TNT 9802 Protocol , “Phase II, Open Label, Nonrandomized, Multicenter Study of Interstitial 131 1-chTNT-1/B for the Treatment of Newly Diagnosed Non-resectable GBM or Recurrent Anaplastic Astrocytoma and Glioblastoma Multiforme; Sunil J. Patel, Principal Investigator (role Co-investigator), 12/1/1998 – ongoing; funded by Techniclone Corporation

Publications

Publications (most current, 117 total)

  1. Schmidt TM, DeAndrea-Lezarus IA, Kimmell, KT, Vates GH, Haines SJ, Pilcher WH. For the further training of individuals in neurosurgery: a history of the William P. Van Wagenen Fellowship. Journal of Neurosurgery Apr 27 2018:1-5. PMID 29701542
  2. Darrow DP, Quinn C, Donguyen HT, Hunt M, Haines SJ. Creation of an EVD registry from a quality improvement project. World Neurosurgery (2018), doi: 10,1016/j.wneu.2018.03.018. PMID 29545219
  3. McPheeters MJ, Talcott RD, Hubbard ME, Haines SJ, Hunt MA. Assessing the accuracy of neurological surgery resident case logs at a single institution. Surg Neurol Int 2017: 8:206. Published online 9/6/17. PMID 28966813
  4. Webb AJ, Ullman NL, Morgan TC, Muschelli J, Kornbluth J, Awad IA, Mayo S, Rosenblum M, Ziai W, Zuccarello M, Aldrich F, John S, Harnott S, Lopez G, Broaddus WC, Wijman C, Vespa P, Bullock R, Haines SJ, Cruz-Flores S, Tuhrim S, Hill MD, Narayan R, Hanley DF, MISTIE and CLEAR Investigators. Accuracy of the ABC/2 score for intracerebral hemorrhage: Systemic review and analysis of MISTIE, CLEAR-IVH, CLEAR III. Stroke 2015; 46(9):2470-6. PMID 26243227
  5. Nelson KS, Brearley AM, Haines SJ. Evidence-based assessment of well-established interventions: The parachute and the epidural hematoma. Neurosurgery 2014; 75: 552-559. PMID:25050576
  6. Norby K, Siddiq F, Malik M, Haines SJ. The effect of duty hour regulations on outcomes of neurologic surgery in training hospitals in the United States: duty hour regulations and patient outcomes. J Neurosurg 2014; 3:1-15. PMID 24888763
  7. Haines SJ, Rockswold GL, Maxwell RE. 75 Years of Neurosurgery at the University of Minnesota. Neurosurgery 2014; 74(5): 553-560. PMID 24521612
  8. Janson C, Romanova LG, Rudser K, Haines SJ. Improvement in clinical outcome following optimal targeting of brain ventricular catheters with intraoperative imaging. J Neurosurg 2014; 120 (3):684-96. PMID:24116721
  9. Olin MR, Low W, McKenna DH, Haines SJ, Dahlheimer T, Nascene D, Gustafson MP, Dietz AB, Clark HB, Chen W, Blazar B, Ohlfest JR, Moertel C. Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4+IL17+ response. Journal for ImmunoTherapy of Cancer 2014, 2:4 doi:10.1186/2051-1426-2-4 PMID 24829761
  10. Osbun JW, Ellenbogen RG, Chesnut RM, Chin LS, Connolly PJ, Cosgrove GR, Delashaw JB Jr, Golfinos JG, Greenlee JD, Haines SJ, Janno J, et al. A multicenter, single-blind, prospective randomized trial to evaluate the safety of a polyethylene glycol hydrogel (duraseal dura sealant system) as a dural sealant in cranial surgery. World Neurosurgery 2012; 78 (5):498-504. PMID 22381303

Other Articles, Editorials, Reviews

  1. Lim JJ, Ladd BM, Grande AW, Haines SJ. Letter: Prepackaged instrument kit for percutaneous balloon compression rhizotomy for the treatment of trigeminal neuralgia: Improvised solution for an unexpected national supply shortage. Operative Neurosurgery, 2017:13 (4) E19-E20. PMID 28838119
  2. Haines SJ. Principles and practice of pediatric neurosurgery, 2nd ed., Book Review, Ped Neurol 2008; 39 (1): 71-72.
  3. Bruns P, Halbert K, Trusheim J, Haines SJ. Neurosurgical oncology: tumors and treatments. Masonic Cancer Center News Spring 2008, Vol 32, Issue 1.
  4. Haines SJ. Editorial: How to choose your neurosurgeon. Pract Neurol 2010; 10:2-3. PMID 20130290
  5. Haines SJ. Shunt infection. J Neurosurg 2007; 106:((1 Suppl):13-4.
  6. Haines SJ. Lyle A. French, MD, PhD, 1915 – 2004 – Obituary. J Neurosurg 2005; 102(5):956-957.
  7. Haines SJ, Walters BC, Florin RE, Harbaugh RE. Guidelines or potentially dangerous recommendations? J Neurosurg 1998; 89(4):687-688. PMID 9761072
  8. Malis LI, Ruberti RF, Kaufman AB, Kanpolat Y, Peter JC, Haines SJ, Blanot S, Cinalli G, Meyer P, Pierre-Kahn A. Intraoperative antibiotic prophylaxis. Surg Neur 1997; 47(5):481-483.
  9. Haines SJ. What do we learn from disciplined practice learning? JAMA 1996; 276(6):447. PMID 8691542
  10. Barnett HJ, Haines SJ. Carotid Endarterectomy for asymptomatic carotid stenosis. N Engl J Med 1993; 328:276-279.

Abstracts

  1. Pluhar GE, Chen W, Grogan P, Seiler C, Olin M, Carlson C, Cruz KAS, Castro M, Lowenstein P, Haines SJ, Hnt MA, Ohlfest JR. Antitumor Responses In Dogs With Spontaneous Astrocytoma And Papillary Meningioma Treated By Immunotherapy. Neuro-oncology 2009; 11(5):618, (abstract)
  2. Watanabe Y, Haines SJ. Dosimetric analyses of repeat gamma knife radiosurgery, presented at Society for Neuro-Oncology, 2007; May 15.
  3. Patel SJ, Spicer K, Van Tassel P, Gordon L, Chergey A, Haines SJ. Results in a dose-escalating trial of intra-tumoral infusion with I-131/ch-TNT-1/B in the treatment of recurrent malignant glioma. Neuro-Oncology 1999; 1:S111.
  4. Nussbaum ES, Heros RC, Haines SJ, Erickson DL. Complications And Cost-Effectiveness Of Carotid Endarterectomy at an Academic Center. J Neurosurg 1995; 82(2):A371.
  5. Blount JP, Lushine KA, Haines SJ. Selective dorsal rhizotomy - long-term follow-up in 60 patients. J Neurosurg 1994; 80(2):A390 (abstract).

Books

  1. Haines SJ, Walters BC, eds. Evidence-Based Neurosurgery: An Introduction. Thieme Medical Publishing 2006, pp 237.
  2. Committee on Post Market Surveillance of Pediatric Medical Devices, Safe Medical Devices for Children, The Institute of Medicine of the National Academies, Washington Academies Press, Washington, DC, 2006.
  3. Nelson PB, Haines SJ. Series editors, Concepts in Neurosurgery, Baltimore: Lippincott Williams and Wilkins. 1993 – 2001
  4. Volume 7: Minimally Invasive Techniques in Neurosurgery, 1995
  5. Volume 8: The Molecular Basis of Neurological Disease, 1996
  6. Volume 9: Neurosurgery in Transition, 1998
  7. Volume 10: Cost and Quality in Neurosurgery, 2001
  8. 4.Cohen AR, Haines SJ, eds. Minimally invasive techniques in neurosurgery, Concepts in Neurosurgery, 1995; Vol.7, Williams & Wilkins, pp 286.
  9. 5.Haines SJ, Heros RC, eds. Brain stem surgery, Neurosurgical Clinics of North America, W.B. Saunders,1993; pp 357-598.
  10. 6.Haines SJ, Hall WA, eds. Infections in neurological surgery, Neurosurgical Clinics of North America, W. B. Saunders,1992; pp 259-496.

Books (pending)

  1. Haines SJ, Glantz MJ, Smith DB, eds. Evidence-Based Neurosurgery: From Concept to Practice: Second Edition. Thieme Medical Publishers, Inc. Nov 2015.

Invited Book Chapters (most current, 50 total)

  1. Haines SJ, Partington MD. Clinical research in quality improvement: Complementary approaches to improving neurosurgical practice, in Guillaume DJ, Hunt MA, eds. Quality and Safety in Neurosurgery, San Diego: Academic Press, 2018; pp. 25-36
  2. Haines SJ. Evidence-based practice of neurosurgery: Implications for quality and safety, in Guillaume DJ, Hunt MA, eds. Quality and Safety in Neurosurgery, San Diego: Academic Press, 2018; pp. 97-106
  3. Darrow D, Quinn C, Haines SJ, Hunt MA. Creating national practice standards through collaboration, in Guillaume DJ, Hunt MA, eds. Quality and Safety in Neurosurgery, San Diego: Academic Press, 2018; pp. 257-268
  4. Miller C, Garton H, Barker II FG, Haines SJ. Neurosurgical epidemiology and outcomes assessment, in Youmans Neurological Surgery, 7th ed., H. Richard Winn, editor, Elsevier Saunders, Chapter 57, p. 378, e456-473, 2017
  5. Vasquez C, Jones KE, Hunt MA, Haines SJ. Use and misuse of antibiotics, in Youmans Neurological Surgery, 7th ed, H. Richard Winn, editor, Elsevier Saunders, Chapter 38. pp 340-348. 2017
  6. Vasquez C, Jones KR, Hunt MA, Haines SJ. The use and misuse of antibiotics, Winn HR, ed. Youmans Neurosurgical Surgery, 7th ed, H. Richard Winn, editor, Elsevier Saunders, Chapter 38, pp 340-348, 2017
  7. Haines SJ. Preserving hearing in the last hearing ear of patients with neurofibromatosis type 2, in Controversies in Neurosurgery, 2nd ed., Osama Al-Mefty, MD, editor, Thieme Publishing, Chapter 5, 2013; pp 76-79
  8. Kainth DS, Terzic D, Haines SJ. Neurosurgical Antibiotic Prophylaxis in Hall WA, Kim PD, eds. Neurosurgical infectious disease: surgical and non-surgical management. Thieme. New York, 2013; pp. 185 – 195
  9. Garton H, Barker II, F, Haines SJ. Neurosurgical epidemiology and outcomes assessment, in Youmans Neurological Surgery, 6th ed., H. Richard Winn, editor, Elsevier Saunders, Chapter 11, 2011; pp. 183-202
  10. Kainth K, Hunt M, Haines SJ. Use and misuse of antibiotics, in Youmans Neurological Surgery, 6th ed, H. Richard Winn, editor, Elsevier Saunders, 2011; Chapter 42. pp 578-587

Invited Lectures (most current, 151 total)

  1. Haines SJ. Management of Cranial Incidental Findings, Panelist, presented at the American Association of Neurological Surgeons, New Orleans, LA, April 30 – May 2, 2018
  2. Haines, SJ. Introduction of 2018 Van Wangenen Lecturer, at the American Association of Neurological Surgeons, New Orlean, LA, April 30 – May 2, 2018
  3. Haines SJ. Management of Cranial Incidental Imaging Findings, Panelist, Breakfast Seminar 220, presented at the American Association of Neurological Surgeons, Los Angeles, CA, April 22-26, 2017
  4. Haines SJ. Trigeminal Neuralgia and Hemifacial Spasm: Management and Results, Panelist, Main Topic12, presented at 27th Annual NASBS Meeting, New Orleans, LA, Mar 3-5, 2017
  5. Haines SJ. Vestibular Schwannoms: Controversies in Modern Management, Panelist, Expert Debate I, presented at 27th Annual NASBS Meeting, New Orleans, LA, Mar 3-5, 2017
  6. Haines SJ. ICP & EVD, Moderator - Scientific Session II, Minnesota Neurosurgical Society Meeting, St. Paul Hotel, St. Paul, MN October 7-8, 2016
  7. Haines SJ. U of M Update, Lecturer, presented at the Minnesota Neurosurgical Society Meeting, St. Paul Hotel, St. Paul, MN, October 7-8, 2016
  8. Haines SJ. Management of Cranial Incidental Imaging Findings, Breakfast Seminar, presented at 82nd American Association of Neurologic Surgeons, Chicago IL, April 30 – May 4, 2016
  9. Haines SJ. Assessment of the Trial Design/Level of Evidence, Panelist, Plenary Session III, presented at 82nd American Association of Neurologic Surgeons, Chicago IL, April 30 – May 4, 2016
  10. Haines SJ. Distinguished Lecture, The making of many neurosurgeon, Lecturer, presented at the Minnesota Neurosurgical Society Meeting, St. Paul Hotel, St. Paul, MN, September 19, 2015.

Scientific Presentations (most current, 96 total)

  1. Haines SJ. Trigeminal neuralgia: Medical and surgical options for treatments. Presented at Annual Updates in Neuroscience for Primary Care, Bloomington, MN, March 24, 2018
  2. Haines SJ. Pediatric Neurosurgical Emergencies. Presented at 9th Annual Avera Brain and Spine Institute Conference, Sioux Falls, SD, March 11, 2016
  3. Haines SJ. The Ethics, Law, and Humanities Committee, a joint committee of the American Academy of Neurology, American Neurological Association and Children Neurology Society, the Ethical Permissibility of Physician Assisted Suicide (PAS). The American Academy of Neurology, Mpls, MN. September 25, 2015
  4. Haines, SJ. Presentation of Complications, The American Society of Pediatric Neurosurgery, Fairmont Orchid, Big Island, Hawaii, January 25-30, 2015
  5. Haines SJ. The Role of an FDA Panel Member in the Regulatory Process, presented at the Design of Medical Devices Conference, Minneapolis, MN, April 13-15, 2010
  6. Haines SJ. Peter J. Jannetta, M.D., Festschrift – Celebrating Four Decades of Neurological Innovation. Magovern Conference Center of Allegheny General Hospital, Pittsburgh, PA, October 12-13, 2007
  7. Haines SJ. Evidence-based Medicine in Neurosurgery: An International Search for Standards, presented at 50th Anniversary Celebration of the Department of Neurosurgery at Seoul National University, Seoul, Korea, August 31-September 2, 2007
  8. Haines SJ. Scientific Session 2: Experiences and Selected Cases. International Symposium on Intra-Operative MRI in Neurosurgery, Houston, TX, July 6-8, 2007
  9. Watanabe Y, Haines SJ. Dosimetric analyses of repeat gamma knife radiosurgery, presented at Society for Neuro-Oncology, May 15, 2007
  10. Campbell, J, Haines, SJ. Radiosurgery versus resection for acoustic neuroma: a decision analysis. NSA/SBNS Annual Meeting, Kiawah Island, SC, April 24, 2002.

Clinical

Clinics

Neurosurgery Clinic;Pediatric Specialty Care-Explorer Clinic

Board Certifications

Neurosurgery

Clinical Interests

Pediatric neurosurgery; Skull-base surgery; Acoustic neuroma; Stereotactic radiosurgery; Trigeminal neuralgia; Hemifacial spasm; Benign intracranial tumors; Spina bifida